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Imazio in a multicenter, double-blind trial, eligible adults with acute pericarditis idiopathic viral, post-pericardiotomy syndromes and pericarditis related to a systemic inflammatory disease were randomly assigned to receive either colchicine at a dose of 0.

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This effect appeared independent of any effect of colchicine on proliferation or invasion and, in contrast to the antimitogenic effect, was reflected in an absolute and stable difference in tumor-free survival in this model, rather than the transient delay in tumor development that may be attributed to the antiproliferative and or anti-invasive effect.

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