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Imazio in a multicenter, double-blind trial, eligible adults with acute pericarditis idiopathic viral, post-pericardiotomy syndromes and pericarditis related to a systemic inflammatory disease were randomly assigned to receive either colchicine at a dose of 0.
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Edward fudman, an austin rheumatologist, told a medical newsletter last year that no one in his specialty had used high doses of colchicine in years.
This effect appeared independent of any effect of colchicine on proliferation or invasion and, in contrast to the antimitogenic effect, was reflected in an absolute and stable difference in tumor-free survival in this model, rather than the transient delay in tumor development that may be attributed to the antiproliferative and or anti-invasive effect.
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